“Pediatric malignant tumors”
Principal investigator: Soledad Gallego Melcom.
Research on the minimal residual disease in the most frecuent pediatric solid neoplasias: neuroblastomas, soft tissue sarcoma and Ewing sarcoma.Molecular classification of soft tissue sarcomas by genetic alteration analysis and by cDNA microarray for gene expression.Characterization of the expression pattern for the new tyrosine hydroxylase isoforms in neuroblastoma and its putative application to study the minimal residual disease.
“Blood diseases and progenitor transplant”
Principal investigator: Juan José Ortega Aramburu.
Epidemiology of acute and chronic leukemia during childhood.
Clinical and genetic manifestations and therapeutic approaches for Fanconi anemia. Prevention, diagnostic and treatment of the bacterial, viral and fungi infections in haematopoietic progenitor transplant. Umbilical cord blood transplant procedure: indications (recommendations, implant prognostic factors, haematological and immunologic reconstitution and complications.
“Transfusion medicine and immunohaematology”
Principal investigator: Pedro Madoz Reano.
Ex vivo expansion of bone marrow for tissue regeneration.
Use of AC133 progenitors from peripheral blood for myocardial regeneration.