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DIGESTIVE TRANSPLANTS RESEARCH GRUP

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Aims

Clinical studies on immunosupression in human liver transplant.
Experimental studies of prostaglandin E1 effect when administered by portal vein on ischemia-reperfusion injuries.
Acute hepatic failure studies in the pig. Use of an arterialized heterotropic auxiliary graft support system. 
Ex situ liver preservation in normothermia.

 

Staff

Head of Digestive Transplants Research Group: Joaquim Balsells Valls
Tel. 93 274 6109 joabalcells@vhebron.net

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Researches
Elena Allende Monclús
Ricardo Andino Cardona
Joaquim Balsells Valls
Silvina Bergamini
Itxarone Bilbao Aguirre
Javier Bueno Aribayos
Joan Cos Trullas
Cristina Dopazo Taboada
Alfredo Escartín Arias
Iñigo López de Cenarruzabeitia
Laura Ocaña Safont
Jorge Juan Olsina Kissler
Silvia Ondategui Parra

Research Areas




“Rejection immunobiology. Immunosupression and tolerance”
Principal investigators: Joaquim Balsells Valls, Itxarone Bilbao Aguirre i Joan Cos Trullas. 
Analyze the mechanisms involved in the phenomena of immunological rejection and in the development of tolerance to the graft, with a special interest in the role of dendritic cells. Clinical trials using either new immunosuppressive drugs or new immunosuppressive protocols.


“Organ preservation and ischemia-reperfusion injury”tdigesti_fig.jpg
Principal investigators: Joaquim Balsells Valls, Antonio Escartín Arias i Iñigo López de Cenarruzabeitia.
Search for new organ preservative solutions and design of new preservative strategy by liver perfusion of normothermic blood. New pharmacologic treatments for ischemia-reperfusion syndrome.



“Acute hepatic failure and liver regeneration”
Principal investigators: Joaquim Balsells Valls, Antonio Escartín Arias i Silvina Bergamini.
A new surgical model for acute hepatic failure has been developed in pig. Hepatocelular support by arterialized auxiliary hepatic transplant. Analyze hepatic regeneration in different experimental models.



“Morbidity and quality of life in liver transplantation”
Principal investigators: Joaquim Balsells Valls, Itxarone Bilbao Aguirre i Javier Bueno Aribayos.
Analysis of factor risks associated with early and long term morbi-mortality in adults and infants undergoing liver transplantation.



“Treatment of Hepatocarcinoma”
Principal investigator: Joaquim Balsells Valls, Antonio Escartín Arias i Lluís Castells Fusté.
Evaluate different treatments for hepatocarcinoma: resection, transplant, percutaneous methods, chemo-embolization and chemotherapy.



“Treatment of colorectal cancer liver metastasis ”
Principal investigator: Joaquim Balsells Valls, Itxarone Bilbao Aguirre i Josep María Tabernero Caturla.
New surgical procedures and chemotherapy.



“Technical advances in hepatobiliopancreatic surgery and transplant”
Principal investigator: Joaquim Balsells Valls, Jorge Juan Olsina.
Evaluation of new technologies: laparoscopy, robotics, image treatment.



 

 


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